What Is Peyronie's Disease?
Peyronie's disease was written about as early as 1678 but was first described in 1743 by Francois Gigot de la Peyronie, a surgeon to Louis XIV of France. Peyronie's disease is a fibrotic tissue disorder or wound healing disorder, which is non-cancerous and is characterized by the presence of excess collagen, which is often called fibrotic tissue or plaque. The most common symptoms caused by the plaque are curvature of the penis and painful erections. It was thought that Peyronie's disease was very rare; however, the rate of reported cases of Peyronie's disease referred to in literature is commonly 3-6%. A recent questionnaire of 8,000 men found the prevalence of the condition to be 1.5% for men age 30-39, 3.0% for men age 40-59, 4.0% for men age 60-69, and 6.5% for men age 70 and older*. The condition has also been diagnosed in patients both younger and older, especially if they are sexually active. The prevalence of Peyronie's disease is likely higher than reported due to patients not seeking diagnosis and treatment. One published study found 22 of 100 autopsied patients to have some degree of the disease process**.
**Gelbard MK, Dorey F, James K. The natural history of Peyronie's disease. J Urol. 1990;144:1376. MEDLINE