Learn More About Peyronie's Disease and
How Transdermal Verapamil 15% Gel Can Help

Treatment Options

Myth: Peyronie's disease resolves in 30% to 50% of patients without treatment. Fact: In the largest published study following patients with no treatment, only 12% had improvement (not cure) in curvature and 48% worsened*.

Doctors have tried many different treatments for Peyronie's disease since it was first described in 1678. The most common treatments can be divided into two basic categories, invasive and non-invasive.

Invasive treatments include:

  • Injections of verapamil, interferon, or purified clostridial collagenase into the plaque
  • Various stretching devices
  • Surgery- usually performed as a last resort due to potential unfavorable outcomes such as impotence and loss of penile length. Penile prosthesis is an option if the patient has severe erectile dysfunction.

Non-invasive options include:

  • Transdermal Verapamil 15% Gel
  • Iontophoresis of different drugs
  • ESWT- Extracorporeal Shock Wave Therapy
  • Oral Medications such as vitamin E, colchicine, paraaminobenzoate (Potaba┬«), tamoxifen, and acetyl-L carnitine

Most doctors agree that a conservative approach to treating Peyronie's disease is preferred. As a result, the least invasive options are typically tried first before moving to invasive procedures or surgery in patients suffering from the most significant cases of Peyronie's disease.

*An Analysis of the Natural History of Peyronie's Disease Mulhall JP, Schiff J, Guhring P The Journal of Urology- 2006 06 (Vol. 175, Issue 6)